Uniques are special weapons and armor pieces in Diablo 4 which have impressive stats and confer special powers to class builds.
Although you don’t necessarily need to use these items with your build, they increase the efficiency of the build, making them the best-in-slot item in certain cases.
In Diablo 4 Season 5, you will come across a lot of these Uniques, some of which will be situational, while others that you will be able to use no matter what build you go for. So, here are the best Uniques for all classes in the game.
Best Universal Uniques in Diablo 4
Universal Uniques are the ones that have no class restrictions and can be paired with every possible build in the game.
Tyrael’s Might
This is one of the best Uniques in the game. With this item equipped, whenever you’re at full health, you’ll deal a barrage of divine light whenever you use a skill.
Andariel’s Visage
Not only does this item drop with impressive stats, the Helm also comes with a special ability that whenever you get a lucky hit, there’s a 20% chance of a Poison Nova spawning and dealing Poison damage for 5 seconds.
Harlequin Crest
This is one of the most popular Uniques in the game, and is an item that every single player wants to get their hands on. With this helm equipped, you’ll get 20% damage reduction and +4 to all your skills.
Doombringer
The Doombringer’s Lucky Hit buff gives it a 25% chance to deal bonus shadow damage to enemies, and reduces their damage dealt by 20% for 5 seconds.
Best Barbarian Uniques in Diablo 4 Season 5

The Grandfather
The Grandfather is a very powerful Unique because it increases your Critical Strike Damage by 100% and the other stats that are on this weapon are incredibly high.
Ramaladni’s Magnum Opus
Ramaladni’s Magnum Opus works with almost any Barbarian build but depends upon the total pool for Fury that you have. With this Unique, you’ll deal 0.2% – 0.5% increased damage for every point of Fury that you have, but you’ll lose 10 Fury points per second.
Fields of Crimson
The Fields of Crimson is a 2-handed sword that allows Barbarians to deal increased bleeding damage to a single target through their Rupture skill. Additionally, a blood pool is also formed for 6 seconds, and any enemy standing in that blood pool takes 30% additional damage.
Best Druid Uniques in Diablo 4

Vasily’s Prayer
Vasily’s Prayer converts all your Earth skills into Werebear skills and whenever you cast them, you’re fortified for 2% – 5% of your Maximum Life. Due to this special ability, your Earth skills will also benefit from any bonuses that your Werebear skills have from the Paragon Boards or additional nodes on the Skill Tree.
Tempest Roar
Just like Vasily’s Prayer, the Tempest Roar converts all your Storm skills into Werewolf skills allowing them to benefit from the bonuses the latter gets.
Mad Wolf’s Glee
The Mad Wolf’s Glee is a powerful Unique because it makes your Werewolf form your true form. Meaning you’ll continue to be in your Werewolf state without having to shapeshift into it.
Best Necromancer Uniques in Diablo 4 Season 5

Deathless Visage
Deathless Visage is a must-use Unique with the Bone Spear build because it creates explosive bone spear echoes that gain extra damage based on how much overall Critical Strike Damage you have.
Black River
This Necromancer Unique works best if you have the Corpse Explosion skill equipped. With this scythe equipped, whenever you use your Corpse Explosion skill, it’ll use upto four corpses nearby, and give bonus damage and increased explosion size for every corpse consumed.
Best Rogue Uniques in Diablo 4

Skyhunter
Skyhunter has become one of the best Uniques for Rogues because of its recent buff. However, to get it to work, you’ll have to be using the Precision key passive. With this weapon equipped, the first direct damage you deal on an enemy with a skill, is a guaranteed Critical Hit.
Scoundrel’s Kiss
Scoundrel’s Kiss works well with the Rapid Fire Rogue skill. All it does is randomly lob a set of exploding arrows at a target. This effect happens automatically, and you don’t need to trigger the skill to get this bonus to work.
Cowl of the Nameless
This Rogue Unique is has a very simple bonus. All it does is increase the Lucky Hit chance by 20%-40% on enemies that you’ve crowd controlled. So if you’re running with the Chill Imbuement, this is a good armor piece to use.
Best Sorcerer Uniques in Diablo 4 Season 5

Ring of Starless Skies
The Ring of Starless skies works with any build, and is probably the best Sorcerer Unique because it reduces Resource requirement and increases skill damage whenever you spend your Primary Resource.
Raiment of the Infinite
Raiment of the Infinite works with builds where you’ll be using the Teleport skill a lot. Although it’ll increase the cooldown of the skill by 20%, whenever you use the skill, it’ll pull enemies close to you and stun them for 2-3 seconds.
Tal Rasha’s Iridescent Loop
Tal Rasha’s Iridescent Loop is a Unique that works with almost every Sorcerer build because its special buff revolves around increasing outgoing elemental damage.