Best Python build in The First Descendant

Not only is the Python one of the best weapons in The First Descendant it’s one of the best Ultimates that are currently in the game.

Unlike the other weapons in the game, crafting this weapon is slightly tedious, but given how versatile it is, you can use it with almost every Descendant in the game.

Best Module setup for the Python

ModuleDescription
Sweeping SquadWhen defeating an enemy, Firearm ATK +X% for 5s at a 33% chance (up to 3 Stacks)
SharpshooterFirearm ATK +X%, Firearm Critical Hit Rate +X%
Insight FocusFirearm Critical Hit Rate +X%, Firearm Critical Hit Damage +X%
Weak Point InsightWeak Point Damage +X%, Firearm Critical Hit Rate +X%
Weak Point SightWeak Point Damage +X%
Rifling ReinforcementFirearm ATK +X%
Better ConcentrationFirearm Critical Hit Damage +X%
Better InsightFirearm Critical Hit Rate +X%
Action and ReactionFirearm ATK +X%, Recoil +X%
Bullet RainFire Rate +X%, Firearm ATK +X%
Toxic EnhancementAdds Toxic ATK equal to X% of Firearm ATK

The Module setup for this weapon is very simple. All you need to focus on is increasing the overall critical hit damage that the weapon deals along with the weapon damage, while controlling the recoil.

The Python has a high rate of fire anyway, so you you’ll be shredding through your enemies in no time.

How to get the Python in The First Descendant

The only way you can get the Python in The First Descendant is by crafting it. However, in order to craft the weapon, you will have to first get the blueprints of the different components and then craft them.

Here’s where you can get all the necessary blueprints to craft the Python:

ItemHow to get
Python Blueprint・Intercept Battle: (Common) (Dead Bride) Amorphous Material Pattern: 025 required
・ Verspers (Hard) – Abyssal Void Fusion Reactor – Vespers Ruins
・ Fortress (Hard) – Abyssal Void Fusion Reactor – Fortress Defense Line
・ Sterile Land (Hard) – Abyssal Void Fusion Reactor – Sterile Land Repository
Python Nano Tube Blueprint・Intercept Battle: (Common) (Pyromaniac) Amorphous Material Pattern: 039 required
・ Intercept Battle: (Hard) (Executioner) Amorphous Material Pattern: 059 required
・ Sterile Land (Normal) – Void Fusion Reactor – Sterile Land Repository
・ White-night Gulch (Hard) – Abyssal Void Fusion Reactor – White-night Gulch Hatchery
Python Polymer Syncytium Blueprint・Intercept Battle: (Common) (Devourer) Amorphous Material Pattern: 029 required
・ Intercept Battle: (Common) (Swamp Walker) Amorphous Material Pattern: 044 required
・ Kingston (Hard) – Abyssal Void Fusion Reactor – Kingston Grand Square
・ Agna Desert (Hard) – Abyssal Void Fusion Reactor – Agna Desert Vermilion Waste
Python Synthetic Fiber Blueprint・Intercept Battle: (Common) (Grave Walker) Amorphous Material Pattern: 005 required
・ Intercept Battle: (Common) (Stunning Beauty) Amorphous Material Pattern: 096 required
・ Intercept Battle: (Hard) (Swamp Walker) Amorphous Material Pattern: 096 required
・ Intercept Battle: (Hard) (Obstructer) Amorphous Material Pattern: 105 required

Once you’ve unlocked these blueprints, you’ll have to craft them using the following materials:

  • 1x Python Polymer Syncytium
    • 97x Hardener
    • 91x Nanopolymers
    • 11x Crystal Biogel
    • Python Polymer Synctium Blueprint
  • 1x Python Synthetic Fiber
    • 108x Silicon
    • 73x Flectorite
    • 10x Positive Ion Particle
    • Python Synthetic Fiber Blueprint
  • 1x Python Nano Tube
    • 62x Monad Shard
    • 102x Ceramic Composite
    • 8x Conductive Metallic Foil
    • Python Nano Tube Blueprint

After you get all these items, you will finally be able to craft the weapon. It’ll cost you 100,000 Gold and you will have to wait for 4 hours before you can start using the weapon, but you’ll have to reach Mastery Rank 10 to unlock the research for this weapon.

Best Descendants

The weapon is so versatile that you can use it with any Descendant that you’ve unlocked. However, since the Python makes enemies more susceptible to Toxic damage, Freyna is the best one to use with it.

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