League of Legends best Vayne build guide: Runes, Itemization, Strategy, and more

On-hit ADCs have been doing pretty well in season 14 with the new League of Legends item updates bringing some quality-of-life improvements to the best Vayne build in the Top and Bot lane. Vayne is a hyper carry that can take over team fights in the late game, however, she is pretty hard to master and will usually take you some practice to get used to her kit.

Fortunately, the Night Hunter can be a very rewarding experience when played right. Her 1v1 power is unparalleled and very few ADCs come with the outplay potential that she brings to the table.

League of Legends season 14’s best Vayne build sees some significant itemization changes allowing her more damage uptime the later the game goes.


Contents


League of Legends 14.11 Best Vayne On-hit build (Bot Lane/ADC)

Runes 

Vayne runes
PrecisionResolvePassive Stats
Press the AttackConditioning+10% Attack Speed
TriumphOvergrowth+9 Adaptive (5.4 AD or 9 AP)
Legend: Alacrity+10% Tenacity and Slow resist
Coup de grace

Itemization

Core Build (On-hit)Alternate Build Path (Crit)Situational Items
Blade of the Ruined KingKraken SlayerRanduin’s Omen
Berserker’s GreavesBerserker’s GreavesKaenic Rookern
Guinsoo’s RagebladeInfinity EdgeForce of Nature
TerminusPhantom DancerThornmail
Wit’s End Lord Dominik’s RegardsEssence Reaver
Guardian AngelImmortal ShieldbowTrinity Force

Spells

  • Flash
  • Heal

Skill Unlock Priority

Vayne TumbleQ: Tumble1101213
Vayne SilverBolts W: Silver Bolts2457 9   
Vayne condemn E: Condemn3        14151718
Vayne Final Hour R: Final hour61116

League of Legends 14.11 Best Vayne Top build

Vayne Top Runes

Runes 

ResolvePrecisionPassive Stats
Grasp of the UndyingLegend: Alacrity+10% Attack Speed
DemolishCoup de Grace+9 Adaptive (5.4 AD or 9 AP)
Second Wind+10-180 HP (Levels 1-18)
Overgrowth

Itemization

Core BuildSituational Items
Trinity ForceWit’s End
Blade of the Ruined KingChempunk Chainsword
Titanic HydraSpirit Visage
Randuin’s OmenForce of Nature
Berserker’s GreavesRanduin’s Omen
Kaenic RookernThornmail

Spells

  • Flash
  • Teleport

Skill Unlock Priority

Vayne Tumble Q: Tumble18  101213
Vayne SilverBolts W: Silver Bolts2457 9   
Vayne condemn E: Condemn3        14151718
Vayne Final Hour R: Final hour61116

League of Legends 14.11 Best Vayne Lethality build

Runes 

Vayne runes
PrecisionResolvePassive Stats
Press the AttackConditioning+10% Attack Speed
TriumphOvergrowth+9 Adaptive (5.4 AD or 9 AP)
Legend: Alacrity+10% Tenacity and Slow resist
Coup de grace

Itemization

Core BuildSituational Items
StormrazorMaw of Malmortius
Berserker’s GreavesMercurial Scimitar
Voltaic CycloswordEdge of Night
Youmuu’s GhostbladeGuardian Angel
Essence ReaverImmortal Shieldbow
TerminusKaenic Rookern

Spells

  • Flash
  • Ghost

Skill Unlock Priority

Vayne Tumble Q: Tumble18  101213
Vayne SilverBolts W: Silver Bolts2457 9   
Vayne condemn E: Condemn3        14151718
Vayne Final Hour R: Final hour61116

Vayne Pros and Cons in League of Legends Season 14

Pros:

  • Bot Lane: On-hit Vayne is a hyper-carry who can take over teamfights once she gets going. With the right support duo, she can be very hard to pin down, and with the true damage she comes with, Vayne can shred through tanks. She is also versatile enough to champion a crit build.
  • Top Lane: Vayne usually counters most top lane tanks in Riot’s MOBA. She is a menace to deal with because of her range and true damage, and will usually push in the lane allowing her access to early tower plates and a lead that she can snowball from. Vayne is also a menace in the side lanes, split pushing with her will often make the enemy team invest resources in dealing with her.

Cons:

  • Bot Lane: Vayne has a very weak early game where she is often countered by ADCs that have more range than her. Aggressive supports like Lux and Brand can also make it difficult for her to get farm, so she often has to rely on CSing under the tower. Her lack of wave-clear prowess also makes it difficult for her to stop an enemy siege.
  • Top Lane: Vayne is very weak to hard CC and her squishy nature makes her easy to gank and kill in the Top Lane. If the jungler and top laner come with a lot of hard CC she will have a hard time getting early leads.

How to play Vayne: Tips and Tricks for League of Legends Season 14

Vayne best ADC to climb rank

Early Game:

  • Bot Lane: Vayne’s early game in the Bot Lane will all be about staying relevant in farm. She is often put ranged by most traditional ADCs which makes it quite difficult for her to have an advantage in lane. So keep up with your creep score and learn to farm under the turret so that you can reach your item power spikes early.
  • Top Lane: Vayne is usually a lane bully against most tank Top Laners. The true damage on her W lets her have a relatively easier time in lane, however, she is susceptible to ganks. If the enemy jungler has a hard CC that can lock you down, you will need to be extra careful of their pathing when pushing the lane. As she will usually gain an early advantage in the Top Lane, look to help your jungler secure the Voidgrubs.

Mid Game:

  • Bot Lane: Once you start hitting your power spikes rotate to the mid lane so that you can help your team contest for the neutral objectives. The goal will be to secure the Rift Herald, Drake, and the first Baron spawn, so be sure to be prepared for a teamfight. Don’t be afraid to peel for your team. Vayne’s W is a tank killer, and you will be able to shred through the enemy front line in a matter of seconds
  • Top Lane: Top Lane Vayne is a bit tankier than her Bot Lane counterpart. This allows her to be a bit more aggressive with her positioning and look to bait in the enemy front line by chipping at them. If your Teleport is up, look to push out the side lanes and threaten tower damage. You can always use the Summoner Spell to join your team if a fight breaks out.

Late Game:

  • Bot Lane: The Late Game is when Vayne becomes a hyper carry shredding through the entire enemy team. But positioning is key as the enemy team will most likely look to focus their engage on her. If you have an Enchanter Support as a duo, you might want to stick with them instead of going off on your own to look for fights. While she will win out on most 1v1 duels, her lack of vision can give the enemy team the opportunity to collapse on her. It’s best to stick with your team and kite around teamfights.
  • Top Lane: While you can stick to with your team and look for fights, as a Top Lane Vayne the best course of action in the Late Game will be to remain in the side lanes and push for tower damage. With the Demolish rune, Vayne can melt through towers, and if she remains unchecked she can take out the Inhibitor as well as a Nexus Tower, or even end the game in one single push.

Vayne Counters, best match-up, Jungle, and Support synergy

Vayne Bot counters: 

She struggles quite a bit against ADCs that outrange her as well as aggressive AP supports.

Vayne Top counters:

  • Gragas
  • Jayce
  • Garen
  • Singed
  • Teemo
  • Yorick

In the Top Lane, Vayne is not good against the above champions.

Bot favorable match-ups:

Vayne will have an easier time in lane against the above bot lane champions.

Top favorable match-ups:

  • Ornn
  • Illaoi
  • Udyr
  • Aatrox
  • Urgot

She has an easier time in lane against the above picks.

Best Vayne Support pairing and synergy

Enchanter supports pair with Vayne the best in Bot Lane.

Best Vayne Top-Jungle pairing and Synergy

  • Ivern
  • Sejuani
  • Taliyah
  • Maokai
  • Lillia

Vayne pairs really well with the above junglers in the Top Lane.

Abhishek Mallick
Abhishek Mallick
Abhishek Mallick is a Senior Columnist at Backdash. He has a Master's degree in English Literature. In his spare time, he is a fighting game enthusiast, who is also addicted to Shin Megami Tensei, Monster Hunter, and League of Legends. He also enjoys reading and sifting through educational documentaries.

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